RTK signalling: from mouse development & pathologies
to new molecular therapies

Generation of knock-in and knock-out mice
Mouse development
Primary mouse embryonic hepatocyte and cortical neuron cultures
Pharmacological treatment in vitro and in vivo
Survival, migration, invasion, differentiation and proliferation assays
Immuno-histochemistry and in situ hybridisation
Biochemistry
ES cell cultures and in vitro differentiation
FACS sorting
Drug screening and discovery (with our collaborators)
In vivo imaging of cancer